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Medical Information

MIRACLE FRUIT SUPPORTING CANCER PATIENTS

STUDIES, PUBLISHED RESULTS AND ARTICLES

Clinical trial underway in Spain

Status - Recruiting

Estimated Study Completion Date - 30 July 2023

Effect of Dried Miracle Berry on the Olfactory-gustative Perception in Malnourished Cancer Patients.

Clinical trial underway in USA

Status - Recruiting

Estimated Study Completion Date - 30 April 2025

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

Treatment of taste alterations in chemotherapy patients using the "miracle fruit": Preliminary analysis of a pilot study

Publication: Journal of Clinical Oncology

https://ascopubs.org/doi/abs/10.1200/jco.2010.28.15_suppl.e19523

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Pilot study of "miracle fruit" to improve food palatability for patients receiving chemotherapy

Publication: Clinical Journal of Oncology Nursing

https://pubmed.ncbi.nlm.nih.gov/23022943/

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Synsepalum dulcificum and varied taste occurring postradiation trial

Publication: Journal of Otolaryngology-Head and Neck Surgery

https://journals.sagepub.com/doi/abs/10.1177/0194599812451426a168

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Complementary and integrative medicines used by cancer patients to cope with chemotherapy-related taste alterations

Publication: Journal of Holistic Nursing and Midwifery

https://hnmj.gums.ac.ir/article-1-1795-en.html

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Smell and Taste Disorders Resulting from Cancer and Chemotherapy

Publication: Current Pharmaceutical Design

Note: To read this paper by three Australian healthcare professionals, you will need to purchase the pdf.

Miraculin is mentioned on page 7, 2nd paragraph.

http://www.eurekaselect.com/article/73732

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Synsepalum dulcificum

Publication: About Herbs, Memorial Sloan Kettering Cancer Center

https://www.mskcc.org/cancer-care/integrative-medicine/herbs/synsepalum-dulcificum

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Austin Health (Victoria, Aust.) trial into how Miraculin impacts sweet, bitter and metallic tastes*

https://www.facebook.com/AustinHealth/photos/%20a.369155516444021/3359019340790942/?type=3

https://cosa.e-newsletter.com.au/link/id/zzzz5d07243ae70c8034Pzzzz4d6ad53547393645/page.html

*Note: This study is temporarily on hold due to COVID-19 disruptions.

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In 2011 ABC Canberra republishes a story from Discovery News on Miracle fruit. Mentioned in the article is Miracle fruit could be helpful to chemotherapy patients whose taste is distorted.

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Miracle Fruit and Chemotherapy

Publication: Tropical Fruit News. Vol 29 No. 3 March 1995 - Rare Fruit Council International Miami RFCI

https://www.growables.org/information/TropicalFruit/MiracleFruitRFCI3.htm

MIRACLE FRUIT AND CANCER

STUDIES AND PUBLISHED RESULTS

Miracle berry as a potential supplement in the control of metabolic risk factors in cancer

Publication: Journal of Antioxidants

https://www.mdpi.com/2076-3921/9/12/1282

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Taste-modifying protein from miracle fruit

Publication: Science Journal

https://www.science.org/doi/10.1126/science.161.3847.1241

TASTE ISSUES IN CANCER PATIENTS

STUDIES AND PUBLISHED RESULTS

Drug-induced taste disorders

Publication: Drug Safety, The Official Journal of the International Society of Pharmacovigilance

https://pubmed.ncbi.nlm.nih.gov/18302445/

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Metallic taste in cancer patients treated with chemotherapy

Publication: Cancer Treatment Reviews

https://pubmed.ncbi.nlm.nih.gov/25499998/

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Metallic taste in cancer patients treated with systemic therapy: A questionnaire-based study

Publication: Nutrition and Cancer

https://pubmed.ncbi.nlm.nih.gov/27925850/

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Taste and smell disturbances in cancer patients: A scoping review of available treatments

Publication: Supportive Care in Cancer

https://pubmed.ncbi.nlm.nih.gov/32734392

MIRACLE FRUIT ANTIOXIDANT ACTIVITIES

STUDIES AND PUBLISHED RESULTS

Antioxidant-rich phytochemicals in miracle berry (Synsepalum dulcificum) and antioxidant activity of its extracts

Publication: Journal of Food Chemistry

https://www.ncbi.nlm.nih.gov/pubmed/24491731

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Contents of phenolics and flavonoids and antioxidant activities in skin, pulp, and seeds of miracle fruit

Publication: Journal of Food Science

https://www.ncbi.nlm.nih.gov/pubmed/21535817

MIRACLE FRUIT IN DIABETES

STUDIES 

Clinical trial in USA

Status - Completed - Unpublished

Actual Study Completion Date - 31 December 2020

Effect of Miracle Fruit Pill Application on Food Likings and Energy Intake in Diabetic or Prediabetic Patients

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Clinical trial underway in Spain

Status - Recruiting

Estimated Study Completion Date - 30 July 2023

Secondary Outcome Measures, Point 10 - Glucose serum concentration will be measured.

Effect of Dried Miracle Berry on the Olfactory-gustative Perception in Malnourished Cancer Patients.

MIRACLE FRUIT AND SALVIA

FEEDBACK

Many people trying Miracle fruit for the first time experience an increase in saliva. Even those who have had Miracle fruit many times, still produce extra saliva just talking or thinking about the experience.

You can get a dry mouth when you take 3 or more medications, imagine eating a dry biscuit, without saliva.

Saliva acts as lubricant for the mouth, allowing the function of speech to be smoother. It is needed to help chew and dissolve food, making swallowing is easier.

Saliva helps with dental hygiene, forming a protective coating on tooth enamel and washes away food and bacteria remaining in the mouth.

Saliva volume will be measured in the Spanish Clinical Trial, Secondary Outcome Measures Point 7.

Effect of Dried Miracle Berry on the Olfactory-gustative Perception in Malnourished Cancer Patients.

MIRACLE FRUIT AND NAUSEA

FEEDBACK

In the Palm Beach (Florida, USA) Rare Fruit Council's newsletter in 1994/1995 it was reported taking Miracle fruit could relieve nausea in cancer patients.

https://www.growables.org/information/TropicalFruit/MiracleFruitRFCI3.htm

So far no medical research has been undertaken, though we have had some customers get relief.

"Chris & Karen thank you for your Product. I am in remission from Oesophageal Cancer. Following the operation, Chemo & Radio Therapies I have had issues with Nausea especially after eating. Having tried Ginger to minimise the symptoms I tried Rubyberry. By the time the cube had dissolved on my tongue the Nausea began to ease & within 10mins had gone completely. I am extremely happy."

- Ivan, Sydney

"Rubyberry Miracle Fruit Cubes really are a miracle! After more than 7 years of endless prescription medications and many natural remedies used to try and ease my daughter's debilitating chronic nausea, I happened to come across Rubyberry.

We were not expecting a cure as we have never had success with anything over the years. However, one afternoon when my daughter was extremely nauseous, I gave her a Rubyberry to try. To our complete surprise and relief, her nausea was gone in 5 minutes! We were overjoyed and so-so happy.

We were sceptical, but the Rubyberry proved us wrong. My daughter has found that only half a cube is enough to completely cure (sic) her serve nausea. It really has been a life-changing miracle for her.
We are so thankful, Rubyberry!"

- Kim, Sydney

MIRACLE FRUIT AND CANCER
TASTE ISSUES IN CANCER PATIENTS
MIRACLE FRUIT ANTIOXIDANT ACTIVITIES
MIRACLE FRUIT IN DIABETES
MIRACLE FRUIT AND SALVIA
MIRACLE FRUIT AND NAUSEA
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